KMID : 0853020180210010022
|
|
Journal of Korean Burn Society 2018 Volume.21 No. 1 p.22 ~ p.30
|
|
Pathological Analysis of Post-Burn Hypertrophic Scars according to Various Scar Ages
|
|
Lee Mi-Young
Kim Hyun-Chul Shin Eun Kwak In-Suk Choi Young-Hee
|
|
Abstract
|
|
|
Purpose: This study investigated the morphological characteristics of hypertrophic scars of various ages.
Methods: This was a retrospective study. Tissue samples from 170 normal skin (control) and 126 scar tissue after undergoing conservative treatment (CT) (n=62) or split thickness skin graft (STSG) (n=64) were obtained. Time from injury (CT) or surgery (STSG) was grouped into periods as follows: first 6 months (period 1), 7¡12 months (period 2), 13¡24 months (period 3), 25¡120 months (period 4), £¾120 months (period 5). Epidermal thickness (ET), dermal thickness (DT), and dermal collagen fiber thickness and length (CFT, CFL) were measured using an image analyzer.
Results: Scar tissue ET was significantly thicker compared to normal skin (P£¼0.05) and was greatest at period 1. Scar tissue DT was significantly thicker compared to normal skin (P£¼0.05), which increased until period 3 but then decreased afterwards. Scar tissue CFT was significantly thinner compared to normal skin (P£¼0.05) except for period 5. Scar tissue CFL was significantly longer compared to normal skin (P£¼0.05). Significant differences were observed especially in younger scar ET, DT, CFT, and CFL.
Conclusion: These findings may assist to increase the understanding of the pathohistological changes in burn scar tissues over time and provide guidance in receiving burn treatment.
|
|
KEYWORD
|
|
Burns, Cicatrix, Hypertrophic, Pathology
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|